Very possible. We have a sheet of paper on the wall where we tally the number of times that IE has been the bane of our existence. I think that piece of paper keeps a number of profanities out of our source code and stylesheets.
It's okay cause IE is now all about embracing web standards and we know have access to all of the bleeding edge web technologies...oh wait SVG has been around (in other browsers and plugins) for a decade :P