I actually have played around with it! I think Clojure feels a lot more polished, but it's also a lot more rigid, which I could definitely see someone disliking. LFE almost feels a little more like Common Lisp, although that's more to do with Erlang and the BEAM than any specific syntax choice. Plus, of course, you get to work with all that OTP goodness. If had to choose between LFE and Clojure as the only language I ever programmed in again, it would be a really hard tossup. Clojure might have a relatively larger community, but I don't want to give up the BEAM!

The reason LFE didn't do it for me was that Elixir is relatively painless syntax-wise, and has really nice high-level libraries like Phoenix and Ecto that simplify a lot of work. If I don't need the BEAM, than I'd rather have a more strictly functional language like Clojure, or something more low-level like Common Lisp. LFE doesn't occupy a niche in my personal ecosystem. That being said, I'd definitely give it another try sometime, and I'd recommend it to anyone else who wants to feel the power of the BEAM.