If the reproduction rate is kept low enough for an extended time, the virus eventually extinguishes itself. With vaccination, "self-vaccination" among the uncooperative, sanitation, testing, contact tracing, and some fraction of the population continuing to take personal measures, the combination can bring the rate down low enough.

The optimist in me hopes that today's anti-vaxxers are just the current incarnation of Luddites. We've had resistance to new ideas for probably the entirety of human history. I mean Galileo was persecuted for heresy. Irrational dogma eventually fades into history.

We can but hope.

people don’t just flip a coin and say “heads, i won’t cooperate”. they all have their own reasons for not cooperating. very few of those reasons are “i flat out don’t want this virus to be eradicated”. so address their concerns, and problem solved.

i’m not claiming it’ll be easy, and i don’t think it’s practical within the short span of a few years, but it’s not impossible.