That is is big problem - good to recognize it as such.
I can tell because the article, though lengthy, never seems to state an explicit problem to be solved. Rather, various ways to apply technology to a field are discussed.
This is a recipe for failure. You need 3 things:
1. a problem to be solved
2. a customer who has that problem
3. money in the customer's pocket waiting to be transferred to yours
The article never even gets to (1).
Regarding (2), if academic groups are the target customer, you're going to have a bad time. They have little money and they tend to be all to happy to build something that sort-of replicates the commercial product you've created for them.
This leaves scientific for-profit companies. They have lots of problems (and these days money), but these problems tend to be quite difficult to discover and solve because of the extensive domain and industry knowledge required.