Yes, I have. And although Microsoft claim otherwise, I find intellisense sorely lacking in a lot of areas. Indexing is bad, search is bad, and their refactorings miss the mark a lot of the time. It's clear that Jetbrains lexical analysis is a lot better. I can search for implementers, find usages, rename and restructure without thinking twice, most of the time.
ReSharper has been really slow, yes, but it's also much better than intellisense and noticably better than Visual Assist. As of now, it's at least usable for me. Have to turn off full solution scanning, but other than that it works.
I agree that the general experience is degraded by ReSharper, sometimes severely, but VS is just too dumb without it, IMHO.