The ISS is literally the most expensive physical structure we have ever built, and it's like 5 floating schoolbuses.
Now I'm for walking and chewing bubblegum. But if you believe in opportunity costs and care about navigating that, it feels like the same problem.
Our planet becoming irradiated is actually not a huge problem! It would still be easier to live on Earth than on Mars! An irradiated radioactive hellscape of Earth would still be more survivable than Mars.
(my more nuanced take is that we have so many basic hospitability problems that need solving, and Mars have all of those times 100, so it would be very good if most of those PhDs could focus on those hospitability problems more than the logistics of shooting a bunch of stuff into space for long term transit)