You must work where I work. Symantec Endpoint Protection (of course set to scan at any access), CarbonBlack, Avecto, etc etc etc. And because the people complain about it they install stuff like Nexthink to diagnose performance issues.
Eventually you end with a system that has so much latency on every I/O operation and over 60 ETW traces running you can't even run or finish a WPR trace.