About 6 years ago, however, I switched exclusively to the open-source XSane [1] and it operates my old scanner(s) beautifully, with all features including the transparency unit.
Try it out if you don't have a highly unusual scanner with driver issues. My workflow involves:
1. XSane for scanning (to 16bit TIFF)
2. exiftool [2] to tag my images with full metadata from my notes: camera, lens, aperture, film, datetime etc just like your digital camera would
3. Darktable [3] to manage my library, cropping, sharpening, adjustments, and tagging
It's a little bit of work - but nowhere near as much as taking and processing 4x5in photographs, and the "digital end results" are very satisfactory.
If I may, an example image: https://www.flickr.com/photos/dawidloubser/35944112383
[1] http://www.sane-project.org/ [2] https://exiftool.org/ [3] https://www.darktable.org/