I was effectively in isolation for months due to some health issues (pre covid). I knew I was depressed as well and decided to take some LSD. I've taken it a few times before, never had a bad time. This time, I had. I repeated this a few times with the same results, its gonna be some time before I try it again.

Nobody should just expect psychodelics "cure depression". Its possible they can deepen it in some conditions and we do not really understand it (I hope we will thanks to studies like these). They can help, but the lesson I got from this is they cannot replace support from fellow humans.

Best advice I can give is try to only do this with some good company, outside on a sunny day, and it is highly likely it will be an overwhelmingly positive experience.