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I, personally, would find this useful for doing work with a photo editor, 3D modelling tool, or some other program where I would otherwise be rapidly switching between keyboard and mouse.

In terms of raw typing speed, I don't think that it can ever come close to the performance of someone using a machine-optimized keyboard layout with two hands, but I very much like the idea of not needing my right hand to dance back and forth between the mouse and the right side of my keyboard.

I could see myself using this in Lightroom where most features can be triggered by a keyboard shortcut but then manipulated (i.e. dragging sliders) with the mouse. It would be faster to have one hand on a full keyboard and the other on my mouse, rather than moving my mouse hand back and forth or using the mouse to invoke all the features.

It seems like a good control surface.

For example in an electronic music context.