~50% increase in firearm deaths: https://www.statista.com/statistics/258913/number-of-firearm...
Major increase in pedestrian deaths and general trend away from walking: https://www.iihs.org/topics/fatality-statistics/detail/pedes...
~4x increase in obesity: https://www.americashealthrankings.org/learn/news/obesity-th...
Major decrease in upward mobility through socioeconomic status: https://www.weforum.org/agenda/2020/09/social-mobility-upwar...
...and a general deterioration of civic institutions, shared culture, and mental health.
Aside from the data, it's subjectively a more fractured and less pleasant country.