Well, you could buy a MacBook Air. Actually, I'd like to see an external GPU over Thunderbolt possibly built into the next line of cinema displays, which would remove the need for the GPU in the Pro line.
Forgive my lack of a source, but was there not an article (maybe on Anandtech?) about high-end cards being 90%+ as performant on a 4x PCI-e slot?
Tests that have been done comparing the performance of relatively high end desktop cards on 1x, 4x, 8x and 16x slots have established that while there is a performance penalty, such a solution would still out perform most mobile GPUs.
http://www.techpowerup.com/reviews/AMD/HD_5870_PCI-Express_S...
http://www.techpowerup.com/reviews/NVIDIA/GTX_480_PCI-Expres...
No it would not.