Multi-country taxation is very complicated. You can get a general idea from asking online, but then you REALLY need to talk to an expert in those specific countries unless your business is just so small that the governments involved would never care.
If you don't want to do that, the best/simplest situation is almost certainly incorporating in the place where the founders actually live permanently.
In general, I strongly agree.
In the particular case, however, there could be aspects that speak against it. Planing to have employees from another country might be such an aspect. If your company resides in country A and wants to employ someone from a country B, there are typically three options, but what is actually possible and which rules apply depents on the actual regulation in both countries: a) The easiest is as a contractor. But this might not be legal, if the work-relation has the characteristics of an employment. b) The person from country B gets an employment contract of the company in country A, but is despatched to country B. This often requires that the person has a work visa for country A (unless inside the EU for EU citizens). c) The company establishes a subsidiary company in country B that employs the person.
The first thing I would do is seeking for advise from your local chambers of commerce and then from the foreign chambers of commerce of the countries you are planning to employ people from.
IANAL, of course.
Open the company anywhere the founder(s) is/are. Just pick a reasonable location if you have many options.
The reasons being that you should never run a business without accounting and legal advice, so you will have someone take care of it for you, and the cost will always cover the risk of doing it yourself poorly.
And when you’re successful, you can always hire more legal/accounting or relocate.
I’ll conclude a bit more harshly: If you’re somehow relying on the costs of operations to balance the success of your company, you might as well just reconsider.