- Does not have a family (no time otherwise)
- Does not have a full-time job
- Spends an extraordinary amount of time Very Online (aka on reddit)
Those are all coupled extremely tightly with a variety of mental health disorders, and you end up with a disproportionate number of people who are anxious, neurotic, bipolar, depressed, and with gender spectrum disorders.
It's also not really based on hard facts, as I doubt that Reddit releases statistics about their mods sexualities.
All in all, making an off-topic comment which is just insulting trans people is maybe not the kind of comment we want to see on HN. Ironically, I could see such a comment gaining traction on certain subreddits.
I did want to separate out the fact that it was needlessly offensive (true) from the truth of the underlying claim about the distribution (which probably true).