Do you provide any context on the normally expected day-to-day variability in CRP levels? I imagine that getting spot checks once a month would require a few years (or perhaps decades) if data before signal could be reliability differentiated from noise in a given individual.

Have you established anything like this in pre-production testing? At least something as simple as "make no intentional changes to your lifestyle and test monthly for a year," and then institute your recommended lifestyle changes and test for another year? If so, it would be helpful data to make available (in a loud way -- I admit I read your post but haven't perused the website yet).

Are there interventions that lower CRP but have no effect (or negative effects) on health? I agree with other commenters regarding the problems of surrogate markers...