Psilocybin is still something that can be grown/synthesized outside of a lab. Sure, major pharmaceutical companies could synthesize pure psilocybin and sell that as a new treatment in some kind of ideal form but it seem that from a lot of anecdotes posted here as well as many other stories I’ve heard, “normal”, non-lab-produced psilocybe mushrooms can have a profiundly positive effect. This might be what big pharma is seeing as a potential opportunity loss and therefore funding studies that skew results in a less positive way.