Yes. My outgoing email goes out via Sonic's SMTP server, with the SPF records to allow it to have a source address of my own domain. Incoming email goes to my own domains and gets forwarded.
This seems to be trouble-free. The domain is on a cheap shared hosting account. I'm not running a server. I own the domain, and not though the hosting company, so I can switch to another provider if necessary. In 27 years, I've had to do that twice, because the hosting provider went out of business.
This is easy to do, and I don't have to deal with Google. I don't even get much spam. All the spammers seem to be targeting the big services now.
I just looked at my spam folder. I'm regularly being offered dental supplies, large hydraulic sheet metal bending presses, and ammonium sulfate fertilizer. It seems that having your own domain now means you get mostly business-to-business spam. I subscribe to Machine Design, which gets me some heavy industrial marketing, but I have no idea why I get dental supply ads. The fertilizer spams, from China, look like a scam - there's a fertilizer shortage, so that's a spam which might get replies.