I was putting together a lot of detailed posts on topics that interested me, mostly for my own record-keeping, but also hoping to build connections with similarly minded people. Despite making a lot of effort, including setting up a few MeFi meetups IRL, I never really clicked with anyone else on the site (except for one Brooklyn hipster who was really into the Achewood web comic, but that wasn't really enough for a long-term friendship).
Since I wasn't getting anything out of the site socially, the heavy moderation, the occasional private nastygram, and a handful of particularly strident users eventually got to me and I closed my account.