I think colonialism and the discovery of the "new world" with Europeans moving there, multiplying and imposing their culture.
(The Inca Empire was, of course, also an Empire formed by the Inca imposing their culture on other tribes.)
https://en.wikipedia.org/wiki/Francisco_Pizarro
or is it an alternate spelling used in English?
Pizzaro sounds (to an Italian) like an invented word about someone that deals with pizza's.
The interactions between him and the Incas showed he was quite a bit more knowledgeable about strategy than they were.
The Romans also had great success against the illiterate barbarian tribes, despite the latter being much larger and better armed.