In RCV it's safe to put your first choice first if either they're an overwhelming favorite to win, or they're so weak they're sure to get eliminated right away. If it's a close three-way election, you might cause your favorite candidate to lose by ranking them first. It's hard to develop any kind of intuition around how your vote will impact the race in these situations -- I think in the long run voters tend to learn that voting for third parties isn't safe, so two parties continue to dominate.