Gunfire, mmm, don't know. Hand-held, I think you'd have a hell of a time trying to score a hit without tracer bullets, and the bullets which miss will be coming down at speed into central Kyiv. They can perfectly well kill. If you did score a hit, well, I really don't know. Could be it's packed with sensitive internal components - maybe you would at least damage it enough that it would no longer be able to guide correctly to its target. Or maybe it's mainly fuel tank and wing and punching holes in both just before impact makes little difference.
I'd say radar-guided AA gunfire would take such drones out easily, at least when I saw it; but it surely flew to Kyvi at very low altitude, and gained height only at the end.
I wonder if they were piloted in real-time, or if they had on-board guidance?
Damage, I'll see later, when I attend the local impact sites. The bang and smoke were quite a lot less than the missiles from a few days ago.