IIRC, 42 is around the age where the window closes, at least, that's what my physician told me. Regardless, if that gap has closed, it may be some consolation to bring this up to your friends and relations who are on the fence about having kids. Everybody's chuffed to tell others about how they made the right choice for them. Rarely, does one hear from another with the courage to say "I changed my mind, and wish I'd taken another path", particularly in the having-kids domain. When I hear your comments above and think "Is this suffering rooted in a desire to contribute to others?" If so, consider telling those you love and respect about your choice and its consequences. Especially tell those who have the potential to have kids - and be a support system in their lives.