Foremost, my apologies if this is a nonsensical question. I haven't been soaking in the WASM ecosystem enough to know how much WASM is "just" JS versus ... something else.
Caveat aside, I saw one of the commits mention jython, which notoriously has ancient (and probably incredibly incomplete) python 2.x support; do you know if python-wasm would run on top of GraalJS (https://github.com/oracle/graaljs#nodejs-support)?
Separately, do you want issues related to zython.org in the cowasm issue tracker? It returns 405 (method not allowed) over and over on POST https://zython.org/python-wasm-sw/read-signal for me
Or 'normal' Python for that matter.
Values that can be set via maxdigits in sys.set_int_max_str_digits(maxdigits) are also limited to size of int in C.
For the future do your have a plans to support WASI and other modern WebAssembly stuff (like WebAssembly Component Model support f.e)?
One motivation for doing this is to try to get the full Python test suite to pass, including all the functionality that involves subprocesses, posix calls, etc. I've only got to about 85% at this point. It can be a ton of tedious work, but at least Zig helps impose some discipline (e.g, it doesn't let you ignore handling errors until later), and makes it easy to test compilation for all supported targets on every change (due to excellent cross compilation support).