Private messaging is one of the primary use cases for E2E encryption in the entire tech industry.
By the time you're trusting a hosting provider to properly do e2e for you... you've basically already lost the game. At any point they can update what's running and remove any/all protections you think you have.
So again - what is your threat model here? Because it sounds like you want "super convenient" and also "super secure" and those aren't two options you just check off - they're really more like diametrically opposed sides of the same slider.