I mean it literally. Money is a social construct. The joke here being that it's funny/ironic to claim that gender being a social construct is "meaningless" but then turn around and claim that another social construct -- money (which is what the "bottom line" is made of) -- is meaningful.

The fact that something is a social construct doesn't mean it doesn't matter. Heck, once you get past the basic "keep this biological organism alive" level, most of human life is lived within social constructs. That doesn't meant they're not real or not meaningful.

Your assumption is the data is meaningless, yet the data shows that excluding self-reported gender from ad targeting leads to worse ad performance...