It certainly does. Not a knock on Boeing[1], but my least comfortable flight ever was on a Virgin 747 from London to New York. At 194 cm (6”4) I’m tall, but not insanely so. I got a middle seat in the middle section where it was physically impossible to fit my legs. Thankfully, before even taxiing out I was able to move to a bulkhead seat in the family row. Since then I insist on picking the seats (emergency exit row ftw) when travelling with someone.

[1] Though I believe that aircraft manufacturers should require some minimal level of comfort on planes they make.