No, it's fundamentally difficult for human beings. You know why? Take a look at mathematics. It is fundamentally difficult for human beings because it does not fit the model that we grew up with evolutionarily.

Math is just a language, but it's a very difficult language for most human beings to learn because we don't naturally think using those type of expressions.

Lisp was created as mathematical notation for computers. It is based of a language that the most people have difficulty with in school.

I'm good at math, and I have no problem with lisp. I'm just pointing out that it will not be the next big thing because this type of thinking is not easy for most people to get into. Pythonic thinking on the other hand is easy for people to understand.