Malheur: 31k
Harney: 8k
Lake: 7k
Klamath: 68k
Grant: 7k
Baker: 16k
Wheeler: 2k
Jefferson: 24k
Sherman: 2k
Morrow: 12k
Union: 26k
Wallowa: 7k
https://www.oregon-demographics.com/counties_by_population
It'd likely end up like Brexit anyways - these areas don't appreciate just how much tax money is spent supporting them and their "independent" lifestyles. Changing their allegiance to a poorer, smaller state would result in a much lower quality of life for them.