The Mirage in particular actually has a pretty large skylight towards the front of the gambling floor.
For a las vegas style ginormous casino and hotel, many of them have the casino footprint much larger than the hotel footprint. You could have big diffused skylights over much of the gaming area, if you wanted. Of course, you'd augement that with lots of artificial lighting, so it would save energy, but not change the experience of roughly constant lighting 24/7
I read about this many years ago in "Fools Die" by Mario Puzo, which of course is fiction, but I think there may be some truth in there (One of the characters in the book is mostly based on the author himself).
Edit. Found an original quote from the book:
Gronevelt was dressed to go down to the casino floor. He fiddled with the control panel that would flood the casino pits with pure oxygen. But it was still too early in the evening. He would push the button sometime in the early-morning hours when the players were tiring and thinking of going to bed. Then he would revive them as if they were puppets. It was only in the past year that be had the oxygen controls wired directly to his suite.High carbon dioxide levels do have a lethargic effect
Fun fact: Puzo had a serious gambling problem. He did most of his research for The Godfather while gambling in a Las Vegas casino (or several?) and interviewing the manager.
I also wonder if they use to do the same - to some extend - in trains and airplanes, I always feel quite relaxed while traveling by them.
I worked in a small casino and we had a huge front window that you could see south eastward. But yes I'm sure some some people lose track of time it's human nature.
There are also some casinos where there are restaurants above the gambling areas.