So your post about keyboard layouts or databases will more likely be discovered/boosted (even if you have no followers on other instances), because the local timeline and hashtags are more quiet than when you're on a general instance (where your posts drown in the noise). Or compared to, say, sauropods.win, were you more likely reach a geologist than a database admin.
Generally I like to be on two or three instances, so my art doodles go to mastodon.art rather than a tech instance (flooded with AI art). I like to check the local timeline or discovery page of other topic-instances via web occasionally, maybe follow someone there to peek into another bubble. The big instances like mastodon.social are just too much, flooded with random stuff I don't care about.