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Reducing average sitting bout length has as big an impact as exercise. https://www.nature.com/articles/s41569-021-00547-y

> In this Review, we make a case for an approach to preventing and managing cardiovascular disease that involves ‘sitting less and moving more’.

Its not just 'Reducing average sitting bout length ' though right ?

Also this seems like self reported observational studies?

Right, both exercise and sitting bout length independently are important. You just can't completely exercise away the impact of sitting alone.