Developers would have to port their games, but I don't see any reason why it wouldn't work. The only real obstacle is a lack of first-party input devices.

The Vision Pro? I'm not a game player generally, I bought my Quest 2 for exercise apps and as a platform for investigating developing for VR and working inside the new medium.

I agree with your implication this is not an appropriate price format for gaming, but I would have thought the Vision Pro is aimed at more of that latter market; though presumably future less premium models will aim at the gaming and more natural consumer markets, or gaming will emerge as a secondary use for the more expensive models like this.