> Consider offering APE for x64 but then still producing ARM binaries the old fashioned way.
The recent version of cosmopolitan generates ARM binaries for Linux and MacOS (https://github.com/jart/cosmopolitan#arm; mode aarch64). There is also blink that provides the x86-64 emulation layer for (APE and other) binaries on a variety of platforms (https://github.com/jart/blink).