But that can happen after or before the valley, and I personally think they're still before it. It's closer to a cartoon or animated being like Wall-E than to a real human.
The rendering being cartoon-like or the shading not being realistic has nothing to do with it.
For me, this goes nowhere near the uncanny valley, for the reason icebraining points out. The coloring and visual tone of the whole piece says "cartoon" to me. It's a different aesthetic than, say, Tangled, but the effect is the same for me. Perhaps this is partly because, as a frequent gamer, that aesthetic is very familiar to me.
I chose to stop watching about half way through. It made me feel very, very uncomfortable. This has to be near the nadir of my familiarity/revulsion curve. I can't explain why, but that's how I felt.
Obviously many people enjoyed watching the Final Fantasy movies as well as the Polar Express movie, and many will enjoy watching Tintin. I can barely get through the ads for these movies. Even the short Tintin preview is cringe inducing to me.
I'd be interested to know more about the tech - is there much pre-rendering going on? How reactive could this be to human users?