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Would you say the same to "Oh, man!", "C'mon man", "man alive", or even (in context) "man overboard"?

I don't think these phrases are referring to the subject they are addressing.

I would drop it where an interlocutor is specifically referenced. So 'oh man' is ok. But c'mon man usually expresses disagreement with a specific person. So while I would certainly say c'mon man to a trans or cis masc (which, if I had any shadow of a doubt, I would determine by querying their pronouns, after sharing mine so as not to inadvertently put them on the spot), I would definitely not say it to a trans or cis fem, and also not to an enby.

Someone's life obviously takes priority over gender sensitivity :)

Again, I realize it's a bit of (cognitive) work, and takes some getting used to. But this is hacker news - a certain intellectual pedigree is assumed.

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