A lot of the comments on the original post suggest that keyboard shortcuts are an impediment to adoption. I type in Dvorak, use Vim with hjkl (actually, jkhl, which I find easier because vertical movement is on my left hand and horizontal on my right), and I make copious use of other shortcuts.
The answer is: you just start using them in their new locations. It doesn't take long for your muscle memory to adjust, and today (~2 years after switching) I can't remember the last time I had to think twice about j,k,h,l, ctl-p, ctl-n, ctl-a, ctl-e, cmd-c, cmd-x, cmd-v, or any other common shortcut.
Don't use a variant that reverts to QWERTY when you hold the command key or something silly like that---you'll just confuse yourself and slow down your adoption.