Very true, IMO one of the reasons why the internet is so toxic is because humans aren't actually interacting directly with each other - we just fire off our thoughts into the ether from behind our screens.

I'd think we're not utilizing all of our social faculties we otherwise would in a face-to-face conversation. We don't see a human in front of us so our brains aren't "firing on all cylinders". E.g. being polite, assuming good-faith, tempering negative impulses and all of the other social lubricant that normally allows humans to peacefully coexist in a society.