Reminder, you can exclude any site from search results on at least Google and DDG, e.g. '-site:fandom.com' will exclude *.fandom.com from results.

There's also a 'ublacklist' extension which lets you block sites from search results as well. I think this edits the results to erase matched sites, though - you're not communicating to Google, et al. that you don't want to see that site.