Being able to easily use different profiles, I like to have one profile for work and one for personal stuff. Chrome/Edge implementation is really nice, you can have different taskbar icons, different theme, history, bookmarks, etc.
Also, Firefox still supports the original Mozilla concept of multiple profiles (which probably even comes from Netscape 4) which is more or less the same thing as Chromium profiles. IIRC the command line options involved in that are same, except last time I cared about that (~2017) Chromium did not have an GUI profile selection/management dialog