Warfarin is one of the most well known scientifically, but as a practitioner you may not know this because hospitals and insurers are scared to acknowledge the ongoing rate of preventable bad outcomes caused by not accounting for variances in metabolism.

That is to say, if we were to actually start assessing patients’ ability to metabolize warfarin we’d have to confront the fact that a huge number of bad clinical outcomes in the recent past stemmed from not doing this.