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No sample can guarantee it “isn’t happening, though”, let alone a n = 1 one, and the judge was mentioning a hypothetical medical test.

Can you remember a single time in your personal life when someone has given a list of prohibitions joined by "and" instead of "or"?

“Don’t drink and drive” is the canonical example.

That's not a list of prohibitions, though. It's a single prohibition: drink and drive is the one thing you shouldn't do.