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The first human landing on Mars destroys a large section of Mars science forever, because then we can no longer be sure if life traces we find there are indigenous or not.

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Slight nuance. We can most definitely tell if a life source you find there is from mars or not - assuming it has the same dna backbone, sequence comparison can tell exactly when life diverged into the two planets (as it likely did if mars ever had life).

The real danger is that life forms hitchhiking the first humans can totally overwhelm any existing life and completely condemn it.

I'm pretty sure that changes nothing and we can still be absolutely sure what we find there is indigenous or not.

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