Of course. There are many such examples of homebrew kits with tape and TTY; I routinely use a serial port connection as TTY over the 20mA current loop with my briefcase KIM that also has the tape lines brought out to a 1/4" TRS jack, though uploading binaries over the serial link is more handy for testing. The TVT 6 5/8 was an easy to assemble video board, or the cool kids had an MTU 8K RAM expansion that emitted the contents as a 320x200 composite image.

In fact, the AIM-65 was basically a heavily expanded KIM with a LED screen, printer, keyboard and tape all in one box from the factory.