You want to tie them in series first, to increase the voltage and keep the amps as low as possible. 110V or 220V are not dangerous voltages, that's why houses are wired at these higher volts. People all over the world handle cables carrying 220V with very few issues. If you wired the house at 12V-48V, some wire in the wall would catch on fire every-time you wanted to toast a slice of bread, lol.