How exactly are you measuring "return" in this case? Because I feel that would be nearly impossible.
it would have been cheaper to send the astronauts to the moon without returning them to earth
more seriously, the work that went into developing microelectronics returned a lot to the economy.
the human genome project has only just started returning its benefits
the R&D for manned moon missions didn't have much in the way of spinoffs.
[1]:https://books.google.com/books?id=gXYItzQARVoC&pg=PA127&lpg=...
The moon rocks, not so much. We have meteorites that came from moon. And from Mars! I could happily leave aside sending anything more to Mars.