It took decades before there was finally the evidence we have today of the social impacts of leaded gasoline.

Sometimes problems have such a broad scope that the impacts are normative across samples and analysis is very difficult.

For example, we know something is at fault for why developed nations have such high and growing autoimmune diseases compared to less developed nations. But specifically what the culprit is eludes us.

An argument from silence isn't a very compelling argument for the safety of microplastics.