There are a lot of differences between passenger vehicles and trucks. The physical dynamics of articulated vehicles, the mission profile, and social dynamics come to mind. How does a robotruck place cones or flares while it awaits rescue?
Personally, I expect autonomous trucking to be a force-multiplier for humans who were formerly drivers. Such trucks will have sleeper cabs and the human will be there to maintain the vehicle and handle the long tail of tasks (filling tires, cleaning, refueling, repairs, rigging, whatever). You'll get 24-hour operation out of a single human employee because they'll be able to sleep and do other things most of the time. Maybe they'll work a second job as a remote call-center operator.