I have a screen for my simrig (racing wheel and pedals setup almost like a car cockpit) with a wireless keyboard that has a touchpad in it mounted to the rig. On my desk across the room, I have a screen, mouse and keyboard, and the PC that powers that rig. I have to turn one or the other monitor off in order to just use the one mouse next to it on it alone. If this was for Windows also, I would use it to keep the monitors separated with their own input devices.
I could imagine several creative workflows that could use setups separated like this, perhaps in a photo studio or a CNC shop.
Although to be honest, I rarely use the second display. I mainly use it while screen sharing in a meeting so I can have notes and stuff up on my main display.
As in, with every significant (user-magnitude-defined) motion of the mouse, all screens darken/grey-out except for a bright spotlight surrounding your mouse. Allows you to always see where your mouse is even up to near-blindness, as that spotlight is going to be 3-6cm in diameter regardless of the screen resolution, and obvious as heck.
Edit: been looking for a tool like this myself. Still have decent vision, but with six monitors at ≈1.5-2k resolution each, a cursor can go missing, fast. Would love to have cursor highlighting (no stupid Win98 “tail”, thanks) on any mouse movement.