- when the pen goes dry, clean it thoroughly before refilling or replacing the cartridge
Back when I was writing a lot I was able to remember to do that every other time, but these days, it just gets done each and every time.
The other issue is how long a pen can be left with ink in it:
- days are okay - weeks are probably okay - months are not okay
So, unless confident you'll be using it again in a week or two, empty, and flush and dry thoroughly before putting away.
And a final recommendation --- try an italic or stub nib, and get a book on Chancery Italic:
https://sites.google.com/view/briem/free-books
or see: