There is no single or set of standards that can prevent you from having to think critically about a result. Rarely are results so overwhelmingly positive that it's obvious what the result means. In those cases it doesn't matter what method you use anyway. The rest of the time, you should use many methods, be wary of their assumptions and think very hard about what the data is telling you. Realize that you are biased in favor of a positive result and play devil's advocate with yourself. This is very very hard work, and most people don't want to do it, especially when their careers improve when they look the other way